This study aims to explore the impact of interaction with artificial intelligence systems on individuals’ mental health and behavior modification. Using a mixed-method approach combining quantitative and qualitative data, information was collected from employees across various sectors to analyze levels of anxiety and psychological stress associated with the use of these systems. The findings revealed a significant relationship between interaction with intelligent systems and increased psychological anxiety, highlighting the need for designing AI systems that consider users’ psychological aspects. The research provides practical recommendations, including enhancing training programs and psychological support for employees, to achieve a better balance between technological benefits and mental well-being in the workplace.